Using miktex with Rstudio is very easy with the miktex portable app available from http://miktex.org/portable. Steps 1. Follow the instructions from http://miktex.org/portable to download and unzip the miktex portable application in a loccation of your choice. 2. In R write the following code in a script and save it. Note that the E:\\Software-Silo\\Miktex\\miktex\\bin location is the location where I unzipped the miktex portable application. # Install miktex y <- Sys.getenv("PATH") x <- paste0(y,";","E:\\Software-Silo\\Miktex\\miktex\\bin") Sys.setenv(PATH=x) 3. Run Miktex by double clicking the following application "miktex-portable.cmd" in the Miktex main directory. 4. Run step 2 in RStudio to install the path into R environment. 5. Open a new RNW in RStudio to test whether Miktex works . 6. Run Compile PDF in RStudio. It should be just at the top of the RNW file created in step 5. 7. You will now see a PDF file whic...